Endocrine Abstracts

Objective: Growth hormone (GH) has long been known to have neuroprotective properties. Hypophysectomy (Hx) completely abolishes circulating endocrine GH. Also neuronal (non-erythrocyte) haemoglobin beta chain (Hbb) in the hippocampus decreases following Hx while GH infusions and injections robustly increase the levels approximately 2-4-fold in male rat hippocampus. Recently it has been revealed that Hbb protein is present in mitochondria in the mammalian brain. Current investi...